1. Master feeds on google reader (works great on any device)
2. Feeddemon (Windows)
FeedDemon is a great app, it will sync with my google feeds and give me the same view of what I have read and what I have not. You have a better user interface for getting through all that data. I also customize the views to work for the way that I want to fly through all my news. These kinds of user interface tweaks aren't possible with google reader yet, but it will improve. Google reader is a great app and works great on mobile or desktop browsers.
I always use google chrome as my primary browser, it wins the speed race hands down, and supports the critical extensions I need. I have moved of Firefox as my primary browser over 6 months ago. I love the fact that my extensions and data (most of them) sync across every system and even the google netbook.
List of extensions I use:
AdBlock - Version: 2.2.19
Browser Button for AdBlock - Version: 0.0.12
gCast Weather - Version: 2.1.2
Google Translate - Version: 1.2.3.1
Google Voice (by Google) - Version: 2.2.3.4
IE Tab - Version: 1.4.30.4
LastPass - Version: 1.70.11
Lazarus: Form Recovery - Version: 3.0.1
PriceBlink - Version: 2.1
Tweetbeat Firsthand - Version: 0.6.3
Weather Window Beta by WeatherBug - Version: 1.0.5
Woot! - Version: 1.1
Xmarks Bookmark and Password Sync - Version: 0.9.0
Yoono Web - Version: 1.0.0.1
